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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NADOLOL

NADOLOL


ATC C07AA12
ATC C07BA12

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANTIARRHYTHMIC
ANTIANGINAL
ADRENERGIC (BETA) BLOCKER
SYMPATHOLYTICS
BETA-2 ADRENERGIC RECEPTOR INVERSE AGONIST

ORAL

VD 123.5 LITER (65 KILOGRAM)

PPB 86 PERCENT

Cl 11.3 LITER / HOUR (65 KILOGRAM)

HT 22 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

BETA-1 ADRENERGIC RECEPTOR
BETA-2 ADRENERGIC RECEPTOR

Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 -- Beta-2 adrenergic receptor UNIPROT P07550 ADRB2

more at DrugCentral

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