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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
METOCLOPRAMIDE

METOCLOPRAMIDE


ATC A03FA01

METABOLISM
ANTIEMETIC
DOPAMINE ANTAGONISTS
TREATMENT OF SYMPTOMATIC GASTROESOPHAGEAL REFLUX

ORAL INJECTION NASAL

Tmax 1.5 HOUR

F 80 PERCENT

VD 227.5 LITER (65 KILOGRAM)

PPB 30 PERCENT

Cl 22.2 LITER / HOUR (65 KILOGRAM)

HT 5.5 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

DOPAMINE RECEPTOR

D(2) dopamine receptor UNIPROT P14416 DRD2 -- 5-hydroxytryptamine receptor 3A UNIPROT P46098 HTR3A

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