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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
GLIPIZIDE

GLIPIZIDE


ATC A10BB07

METABOLISM
ANTIDIABETIC
HYPOGLYCEMIC AGENTS
SULFONYLUREA

ORAL

Tmax 2 HOUR

F 100 PERCENT

VD 11 LITER

PPB 98.5 PERCENT

Cl 2.1 LITER / HOUR (65 KILOGRAM)

HT 3 HOUR

SOLUBILITY INSOLUBLE IN WATER

ATP-SENSITIVE POTASSIUM CHANNEL OF THE PANCREATIC B-CELL

Sulfonylurea receptor 1, Kir6.2 UNIPROT Q09428 ABCC8

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