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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BIOTIN
| BIOTIN | NATURAL MOLECULE (link) METABOLISM | INJECTION INTRAVENOUS | PDB 1SWR (CORE-STREPTAVIDIN MUTANT W120A IN COMPLEX WITH BIOTIN AT PH 7.5) LIGAND CODE = BTN (link to the list of PDB complexes) Download experimental 3D coordinates of BTN with added hydrogens | Insulin-degrading enzyme UNIPROT P14735 IDE more at DrugCentral | EMA | ||||
