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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DISOPYRAMIDE
| DISOPYRAMIDE | CARDIOVASCULAR | ORAL | Cmax 14.1 MICROMOLAR (PMID18621671) Tmax 2 HOUR VD 33.8 LITER (65 KILOGRAM) PPB 65 PERCENT Cl 3.5 LITER / HOUR (65 KILOGRAM) HT 6.7 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | VOLTAGE GATED SODIUM CHANNEL KV1.5 | Sodium channel protein type 5 subunit alpha UNIPROT Q14524 SCN5A more at DrugCentral | EMA | |||
