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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DANTROLENE
| DANTROLENE | MUSCULO-SKELETAL | ORAL INJECTION INTRAVENOUS | VD 24 LITER (65 KILOGRAM) Cl 1.6 LITER / HOUR (65 KILOGRAM) HT 6 HOUR | RYANODINE RECEPTOR 1 | Ryanodine receptor 1 UNIPROT P21817 RYR1 -- Ryanodine receptor 3 UNIPROT Q15413 RYR3 more at DrugCentral | EMA | |||
