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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FLUCYTOSINE (has an active metabolite)
| FLUCYTOSINE | ANTIINFECTIVES | ORAL | Cmax 271.3 MICROMOLAR Tmax 2 HOUR F 83 PERCENT VD 44.2 LITER (65 KILOGRAM) PPB 4 PERCENT Cl 7.8 LITER / HOUR (65 KILOGRAM) HT 3.6 HOUR | CYTOSINE DEAMINASE | Thymidylate synthase UNIPROT P0CS13 TMP1 -- Thymidylate synthase UNIPROT P12461 TMP1 more at DrugCentral | EMA | |||
