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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METHYLERGONOVINE
| METHYLERGONOVINE | VARIOUS | ORAL INJECTION | Cmax 9.56 NANOMOLAR Tmax 1.12 HOUR F 60 PERCENT VD 56.1 LITER Cl 14.4 LITER / HOUR HT 3.39 HOUR | ALPHA-1 ADRENERGIC RECEPTOR SEROTONERGIC (5-HT2) RECEPTOR PDB 6DRY (STRUCTURAL DETERMINANTS OF ACTIVATION AND BIASED AGONISM AT THE 5-HT2B RECEPTOR) LIGAND CODE = H8D (link to the list of PDB complexes) Download experimental 3D coordinates of H8D with added hydrogens | D(1A) dopamine receptor UNIPROT P21728 DRD1 more at DrugCentral | EMA | |||
