Cheminformatic Tools and Databases for Pharmacology

session 73050 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CYCLOTHIAZIDE DISCONTINUED

CYCLOTHIAZIDE


ATC C03AA09
ATC C03AB09

CARDIOVASCULAR
DIURETIC
ANTIHYPERTENSIVE
POSITIVE ALLOSTERIC MODULATORS OF AMPA-TYPE GLUTAMATE RECEPTORS
POTENTIATOR

ORAL GLUTAMATE RECEPTOR 2

PDB 5WEO (ACTIVATED GLUA2 COMPLEX BOUND TO GLUTAMATE, CYCLOTHIAZIDE, AND STZ IN DIGITONIN)

LIGAND CODE = CYZ (link to the list of PDB complexes)

Download experimental 3D coordinates of CYZ with added hydrogens

Solute carrier family 12 member 3 UNIPROT P55017 SLC12A3

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |