Cheminformatic Tools and Databases for Pharmacology

session 37212 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PROPRANOLOL

PROPRANOLOL


ATC C07AA05
ATC C07FX01
ATC C07BA05

CARDIOVASCULAR
NON SELECTIVE BETA ADRENERGIC ANTAGONISTS
ANTIARRHYTHMIC AGENTS
ANTIHYPERTENSIVE AGENTS
VASODILATOR AGENTS

ORAL INJECTION

Tmax 2.5 HOUR

VD 260 LITER (65 KILOGRAM)

PPB 90 PERCENT

Cl 46.8 LITER / HOUR (65 KILOGRAM)

HT 4.5 HOUR

SOLUBILITY READILY SOLUBLE IN WATER

BETA ADRENERGIC RECEPTOR

PDB 5FUK (CRYSTALLIZATION OF A DIMERIC HEME PEROXYGENASE FROM THE FUNGUS MARASMIUS ROTULA)

LIGAND CODE = SNP (link to the list of PDB complexes)

Download experimental 3D coordinates of SNP with added hydrogens

Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 -- Beta-2 adrenergic receptor UNIPROT P07550 ADRB2

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |