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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CLOMIPHENE

CLOMIPHENE


ATC G03GB02

GENITO
INITIATION OF OVULATION
FERTILITY AGENTS, FEMALE
ESTROGEN RECEPTOR ANTAGONIST
ZUCLOMIPHENE (CIS) HAS A LONGER HALF-LIFE THAN ENCLOMIPHENE (TRANS)

ORAL

Cmax 17 NANOMOLAR (PMID18621671)

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

ESTROGEN RECEPTOR

Estrogen receptor UNIPROT P03372 ESR1

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