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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
THIABENDAZOLE DISCONTINUED

THIABENDAZOLE


ATC D01AC06
ATC P02CA02

ANTIPARASITIC
ANTHELMINTIC
ANTINEMATODAL AGENTS

ORAL

Tmax 1.5 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

FUMARATE REDUCTASE

PDB 1YVM (E. COLI METHIONINE AMINOPEPTIDASE IN COMPLEX WITH THIABENDAZOLE)

LIGAND CODE = TMG (link to the list of PDB complexes)

Download experimental 3D coordinates of TMG with added hydrogens

Tubulin UNIPROT C4PKY4 -- Tubulin UNIPROT F1L005

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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