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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ALLOPURINOL (has an active metabolite)
| ALLOPURINOL | MUSCULO-SKELETAL SYSTEM | ORAL INJECTION | Cmax 22 MICROMOLAR Tmax 1.5 HOUR F 90 PERCENT VD 37.7 LITER (65 KILOGRAM) PPB 3 PERCENT Cl 42.9 LITER / HOUR (65 KILOGRAM) HT 1.5 HOUR SOLUBILITY 8 MILLIGRAM / LITER IN WATER | XANTHINE OXIDASE | Xanthine dehydrogenase,oxidase UNIPROT P47989 XDH more at DrugCentral | EMA | |||
