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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ACETYLCYSTEINE
| ACETYLCYSTEINE |
RESPIRATORY SYSTEM | INHALATION ORAL INTRAVENOUS | VD 30.5 LITER (65 KILOGRAM) PPB 83 PERCENT Cl 7.15 LITER / HOUR (65 KILOGRAM) HT 5.6 HOUR | PDB 2J2P (L-FICOLIN COMPLEXED TO N-ACETYL-CYSTEIN (150MM)) LIGAND CODE = SC2 (link to the list of PDB complexes) Download experimental 3D coordinates of SC2 with added hydrogens | Superoxide dismutase Mn mitochondrial UNIPROT P04179 SOD2 more at DrugCentral | EMA | |||
