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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FOLIC ACID (is an active metabolite)
| FOLIC ACID |
BLOOD | ORAL INJECTION INTRAVENOUS | PDB 4P3R (CRYOGENIC WT DHFR, TIME-AVERAGED ENSEMBLE) LIGAND CODE = FOL (link to the list of PDB complexes) Download experimental 3D coordinates of FOL with added hydrogens | Thymidylate synthase UNIPROT P04818 TYMS more at DrugCentral | EMA | ||||
