| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GLYCOPYRROLATE
| GLYCOPYRROLATE GLYCOPYRRONIUM |
METABOLISM | ORAL INJECTION INHALATION INTRAMUSCULAR INTRAVENOUS TOPICAL | Cmax 10.9 NANOMOLAR Tmax 0.45 HOUR VD 27.3 LITER (65 KILOGRAM) Cl 35.1 LITER / HOUR (65 KILOGRAM) HT 0.83 HOUR SOLUBILITY SOLUBLE IN WATER | MUSCARINIC ACETYLCHOLINE RECEPTOR | Muscarinic acetylcholine receptor M1 UNIPROT P11229 CHRM1 -- Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2 more at DrugCentral | EMA | |||
