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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| HISTAMINE DISCONTINUED
| HISTAMINE | NATURAL MOLECULE (link) DIAGNOSTIC AID | INJECTION | Cmax 38 NANOMOLAR (PMID12092744) Tmax 0.3 HOUR VD 59 LITER Cl 210 LITER / HOUR HT 0.18 HOUR | HISTAMINE RECEPTOR PDB 1AVN (HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH THE HISTAMINE ACTIVATOR) LIGAND CODE = HSM (link to the list of PDB complexes) Download experimental 3D coordinates of HSM with added hydrogens | Histamine H1 receptor UNIPROT P35367 HRH1 more at DrugCentral | EMA | |||
