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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OXYMORPHONE
| OXYMORPHONE | NERVOUS SYSTEM | INJECTION RECTAL ORAL | Cmax 14.8 NANOMOLAR Tmax 0.12 HOUR F 10 PERCENT VD 200.2 LITER (65 KILOGRAM) PPB 11 PERCENT Cl 30.8 LITER / HOUR (EQN) HT 4.5 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | MU-TYPE OPIOID RECEPTOR | Mu-type opioid receptor UNIPROT P35372 OPRM1 -- Kappa-type opioid receptor UNIPROT P41145 OPRK1 more at DrugCentral | EMA | |||
