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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DEXAMETHASONE PHOSPHATE (has an active metabolite)
| DEXAMETHASONE PHOSPHATE |
GLUCOCORTICOID | OPHTHALMIC TOPICAL OTIC INJECTION INHALATION NASAL | GLUCOCORTICOID RECEPTOR PDB 3TC5 (SELECTIVE TARGETING OF DISEASE-RELEVANT PROTEIN BINDING DOMAINS BY O-PHOSPHORYLATED NATURAL PRODUCT DERIVATIVES) LIGAND CODE = 3T5 (link to the list of PDB complexes) Download experimental 3D coordinates of 3T5 with added hydrogens | Glucocorticoid receptor UNIPROT P04150 NR3C1 more at DrugCentral | EMA | ||||
