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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TRIFLUOPERAZINE

TRIFLUOPERAZINE


ATC N05AB06

NERVOUS SYSTEM
ANTIPSYCHOTIC
ANXIOLYTIC
DOPAMINE RECEPTOR ANTAGONISTS
PHENOTHIAZINES

ORAL INJECTION D(2) DOPAMINE RECEPTOR

PDB 3KO0 (STRUCTURE OF THE TFP-CA2+-BOUND ACTIVATED FORM OF THE S100A4 METASTASIS FACTOR)

LIGAND CODE = TFP (link to the list of PDB complexes)

Download experimental 3D coordinates of TFP with added hydrogens

D(2) dopamine receptor UNIPROT P14416 DRD2

more at DrugCentral

EMA

ANSM (in French)

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Chemical Probes Portal

ChEMBL
BindingDB
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