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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was usedPrimary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DORDAVIPRONE

DORDAVIPRONE

ANTINEOPLASTIC
PROTEASE ACTIVATOR
TREATMENT OF PATIENTS WITH DIFFUSE MIDLINE GLIOMA

ORAL

Cmax 7.2 MICROMOLAR

Tmax 1.4 HOUR

VD 450 LITER

PPB 96 PERCENT

Cl 27 LITER / HOUR

HT 11 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

MITOCHONDRIAL CASEINOLYTIC PROTEASE P (CLPP)
DOPAMINE D2 RECEPTOR

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