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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CEFTOBIPROLE (is an active metabolite)
| CEFTOBIPROLE MEDOCARIL | ANTIINFECTIVES | - | Cmax 61.7 MICROMOLAR VD 18 LITER PPB 16 PERCENT Cl 4.98 LITER / HOUR HT 3.3 HOUR | PENICILLIN-BINDING PROTEINS (PBPS) PDB 6VJE (CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PENICILLIN-BINDING PROTEIN 3 (PBP3) COMPLEXED WITH CEFTOBIPROLE) LIGAND CODE = RB6 (link to the list of PDB complexes) Download experimental 3D coordinates of RB6 with added hydrogens | MecA UNIPROT Q7DHH4 more at DrugCentral | EMA | |||
