Cheminformatic Tools and Databases for Pharmacology

session 29556 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DANICOPAN

DANICOPAN


ATC L04AJ09

IMMUNOSUPPRESSANTS
COMPLEMENT FACTOR D INHIBITOR
TREATMENT OF EXTRAVASCULAR HEMOLYSIS (EVH) IN ADULTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)
PREVENTS THE CLEAVAGE OF COMPLEMENT FACTOR B INTO THE BA AND BB FRAGMENTS

ORAL

Cmax 1.14 MICROMOLAR

Tmax 3.7 HOUR

VD 395 LITER

PPB 92.9 PERCENT

Cl 63 LITER / HOUR

HT 7.9 HOUR

SOLUBILITY INSOLUBLE FROM PH 4 TO PH 7

COMPLEMENT FACTOR D

-

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |