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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
RESMETIROM

RESMETIROM

HORMONES
THYROID HORMONE RECEPTOR-BETA (THR-BETA) AGONIST
TREATMENT OF NONCIRRHOTIC NONALCOHOLIC STEATOHEPATITIS (NASH)

ORAL

Cmax 2.23 MICROMOLAR

Tmax 4 HOUR

VD 68 LITER

PPB 99 PERCENT

Cl 17.5 LITER / HOUR

HT 4.5 HOUR

SOLUBILITY 0.44 MILLIGRAM PER MILLILITER AT PH 7.04

THYROID HORMONE RECEPTOR BETA

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