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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LOTILANER
| LOTILANER | ANTIPARASITIC | OPHTHALMIC | Cmax 29.8 NANOMOLAR Tmax 2 HOUR PPB 99.9 PERCENT HT 264 HOUR | GAMMA-AMINOBUTYRIC ACID (GABA)-GATED CHLORIDE CHANNEL | Gaba-gated chloride channel, putative UNIPROT E0V9W2 8233868 more at DrugCentral | EMA | |||
