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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FRUQUINTINIB
| FRUQUINTINIB | ANTINEOPLASTIC | ORAL | Cmax 762 NANOMOLAR Tmax 2 HOUR VD 46 LITER PPB 95 PERCENT Cl 0.8 LITER / HOUR HT 42 HOUR SOLUBILITY 0.9 MICROGRAM PER MILLILITER AT PH 6.8 | VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTORS (VEGFR)-1, -2, AND -3 | - more at DrugCentral | EMA | |||
