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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ZURANOLONE

ZURANOLONE

NERVOUS SYSTEM
NEUROACTIVE STEROID GAMMA-AMINOBUTYRIC ACID (GABA) A RECEPTOR POSITIVE MODULATOR INDICATED FOR THE TREATMENT OF POSTPARTUM DEPRESSION (PPD)

ORAL

Tmax 5.5 HOUR

VD 500 LITER

PPB 99.5 PERCENT

Cl 33 LITER / HOUR

HT 22.15 HOUR

SOLUBILITY PRACTICALLLY INSOLUBLE IN WATER

GABA A RECEPTOR

Gamma-aminobutyric acid receptor subunit alpha-1 UNIPROT P14867

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