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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M QUIZARTINIB (is an active metabolite)
| QUIZARTINIB | ANTINEOPLASTIC | - | Cmax 282 NANOMOLAR Tmax 5.5 HOUR PPB 99 PERCENT HT 136 HOUR | TYROSINE KINASE FLT3 | Receptor-type tyrosine-protein kinase FLT3 UNIPROT P36888 FLT3 more at DrugCentral | EMA | |||
