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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ENMETAZOBACTAM DISCONTINUED
| ENMETAZOBACTAM | ANTIINFECTIVES | INTRAVENOUS | Cmax 627 MICROMOLAR VD 25.26 LITER PPB NEGLIGIBLE Cl 7.6 LITER / HOUR HT 2.6 HOUR | BETA-LACTAMASE PDB 6T35 (CRYSTAL STRUCTURE OF AMPC FROM E.COLI WITH ENMETAZOBACTAM (AAI-101)) LIGAND CODE = M9W (link to the list of PDB complexes) Download experimental 3D coordinates of M9W with added hydrogens | - more at DrugCentral | EMA | |||
