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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PALOVAROTENE
| PALOVAROTENE | MUSCULO-SKELETAL SYSTEM | ORAL | Cmax 398 NANOMOLAR Tmax 3.5 HOUR VD 237 LITER PPB 98 PERCENT Cl 19.9 LITER / HOUR HT 8.7 HOUR | RETINOIC ACID RECEPTOR GAMMA (RAR GAMMA) | Retinoic acid receptor gamma UNIPROT P13631 more at DrugCentral | EMA | |||
