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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
GEPIRONE DISCONTINUED (has an active metabolite)

GEPIRONE


ATC N06AX19

NERVOUS SYSTEM
TREATMENT OF MAJOR DEPRESSIVE DISORDER (MDD) IN ADULTS
5HT1A RECEPTOR AGONIST

ORAL

Tmax 6 HOUR

F 15 PERCENT

VD 94.5 LITER

PPB 72 PERCENT

HT 5 HOUR

SOLUBILITY READILY SOLUBLE IN WATER

5HT1A RECEPTOR

5-hydroxytryptamine receptor 1A UNIPROT P08908 HTR1A

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