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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SORAVTANSINE

SORAVTANSINE
MIRVETUXIMAB SORAVTANSINE-GYNX		NATURAL MOLECULE (link)

ANTINEOPLASTIC
FOLATE RECEPTOR ALPHA (FRALPHA)-DIRECTED ANTIBODY
MICROTUBULE INHIBITOR CONJUGATE
ANTIBODY-DRUG CONJUGATE (ADC)
DM4 IS A MAYTANSINE DERIVATIVE
DM4 DISRUPTS THE MICROTUBULE NETWORK WITHIN THE CELL, RESULTING IN CELL CYCLE ARREST AND APOPTOTIC CELL DEATH
TREATMENT OF ADULT PATIENTS WITH FR ALPHA POSITIVE, PLATINUM-RESISTANT EPITHELIAL OVARIAN, FALLOPIAN TUBE, OR PRIMARY PERITONEAL CANCER

 INJECTION

Cmax 5.2 NANOMOLAR

PPB 99 PERCENT

Cl 13.8 LITER / HOUR

HT 67.2 HOUR

 TUBULIN

 TUBULIN TBB1_HUMAN INHIBITOR P04350EMA

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