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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
REZAFUNGIN

REZAFUNGIN


ATC J02AX08

ANTIINFECTIVES
ECHINOCANDIN ANTIFUNGAL
TREATMENT OF CANDIDEMIA AND INVASIVE CANDIDIASIS
SEMISYNTHETIC LIPOPEPTIDE
INHIBITS THE SYNTHESIS OF 1,3-BETA-D-GLUCAN

INTRAVENOUS

Cmax 15.6 MICROMOLAR

VD 67 LITER

PPB 97.1 PERCENT

Cl 0.35 LITER / HOUR

HT 152 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

1,3-BETA-D-GLUCAN SYNTHASE

1,3-beta-glucan synthase UNIPROT O13428

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