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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DAPRODUSTAT DISCONTINUED
| DAPRODUSTAT | BLOOD | ORAL | Tmax 2.5 HOUR F 65 PERCENT VD 14.3 LITER PPB 99 PERCENT Cl 15 LITER / HOUR HT 2.5 HOUR SOLUBILITY POORLY SOLUBLE IN WATER | HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE HIF-PH1 HIF-PH2 HIF-PH3 | Egl nine homolog 1 UNIPROT Q9GZT9 EGLN1 -- Egl nine homolog 2 UNIPROT Q96KS0 EGLN2 more at DrugCentral | EMA | |||
