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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TAURURSODIOL
| TAURURSODIOL | NERVOUS SYSTEM | ORAL | Tmax 4.5 HOUR PPB 98 PERCENT SOLUBILITY SPARINGLY SOLUBLE IN WATER | PDB 5DLV (CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) WITH TAUROURSODEOXYCHOLIC ACID (TUDCA)) LIGAND CODE = 5D5 (link to the list of PDB complexes) Download experimental 3D coordinates of 5D5 with added hydrogens | Unknown more at DrugCentral | EMA | |||
