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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ZAVEGEPANT

ZAVEGEPANT

NERVOUS SYSTEM
CALCITONIN GENE-RELATED PEPTIDE RECEPTOR ANTAGONIST
TREATMENT OF MIGRAINE

NASAL

Tmax 0.5 HOUR

F 5 PERCENT

VD 1774 LITER

PPB 90 PERCENT

Cl 266 LITER / HOUR

HT 6.55 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

CALCITONIN GENE-RELATED PEPTIDE (CGRP) RECEPTOR

Calcitonin gene-related peptide type 1 receptor UNIPROT Q16602 CALCRL

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