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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M DEUCRAVACITINIB (is an active metabolite)

DEUCRAVACITINIB


ATC L04AF07

IMMUNOSUPPRESSANTS
IMMUNOMODULATING AGENTS
TYROSINE KINASE 2 (TYK2) ALLOSTERIC INHIBITOR
TREATMENT OF ADULTS WITH MODERATE-TO-SEVERE PLAQUE PSORIASIS
BMT-153261 ACCOUNTS FOR APPROXIMATELY 20 PERCENT OF THE SYSTEMIC EXPOSURE

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Cmax 12.1 NANOMOLAR

TYROSINE KINASE 2 (TYK2)

tyrosine kinase 2 (TYK2) UNIPROT P29597

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