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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M DEUCRAVACITINIB (is an active metabolite)
| DEUCRAVACITINIB | IMMUNOSUPPRESSANTS | - | Cmax 12.1 NANOMOLAR | TYROSINE KINASE 2 (TYK2) | tyrosine kinase 2 (TYK2) UNIPROT P29597 more at DrugCentral | EMA | |||
