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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FINERENONE
| FINERENONE | CARDIOVASCULAR | ORAL | Cmax 422.8 NANOMOLAR Tmax 0.8 HOUR F 44 PERCENT VD 52.6 LITER PPB 92 PERCENT Cl 25 LITER / HOUR HT 2.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | MINERALOCORTICOID RECEPTOR | Mineralocorticoid receptor UNIPROT P08235 more at DrugCentral | EMA | |||
