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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VOCLOSPORIN
| VOCLOSPORIN | IMMUNOMODULATING | ORAL | Tmax 1.5 HOUR VD 2154 LITER PPB 97 PERCENT Cl 63.6 LITER / HOUR HT 30 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER (LESS THAN 0.1 GRAM PER LITER) | CYCLOPHILIN A PDB 3ODI (CRYSTAL STRUCTURE OF CYCLOPHILIN A IN COMPLEX WITH VOCLOSPORIN E-ISA247) LIGAND CODE = VOCLOSPORIN (link to the list of PDB complexes) Download experimental 3D coordinates of VOCLOSPORIN with added hydrogens | Peptidyl-prolyl cis-trans isomerase A UNIPROT P62937 PPIA more at DrugCentral | EMA | |||
