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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PONESIMOD
| PONESIMOD | IMMUNOMODULATING | ORAL | Tmax 3 HOUR F 84 PERCENT VD 160 LITER PPB 99 PERCENT Cl 3.8 LITER / HOUR HT 33 HOUR SOLUBILITY PACTICALLY INSOLUBLE IN WATER | SPHINGOSINE1-PHOSPHATE (S1P) RECEPTOR 1 | Sphingosine 1-phosphate receptor 1 UNIPROT P21453 S1PR1 more at DrugCentral | EMA | |||
