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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TOLBUTAMIDE DISCONTINUED
| TOLBUTAMIDE | METABOLISM | ORAL INJECTION | Cmax 217.7 MICROMOLAR Tmax 3.8 HOUR VD 7.8 LITER (65 KILOGRAM) PPB 95 PERCENT Cl 0.819 LITER / HOUR (65 KILOGRAM) HT 7 HOUR | K(ATP) CHANNEL | Sulfonylurea receptor 1, Kir6.2 UNIPROT Q09428 ABCC8 more at DrugCentral | EMA | |||
