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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SERDEXMETHYLPHENIDATE (has an active metabolite)

SERDEXMETHYLPHENIDATE


ATC N06BA15

NERVOUS SYSTEM
PRODRUG OF DEXMETHYLPHENIDATE
CENTRAL NERVOUS SYSTEM STIMULANT
TREATMENT OF ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD)
BLOCKS THE REUPTAKE OF NOREPINEPHRINE AND DOPAMINE

ORAL

Tmax 2 HOUR

F 3 PERCENT

VD 1904.5 LITER (65 KILOGRAM)

PPB 56 PERCENT

Cl 234 LITER / HOUR

HT 5.7 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

SODIUM-DEPENDENT NORADRENALINE TRANSPORTER
SODIUM-DEPENDENT DOPAMINE TRANSPORTER
SODIUM-DEPENDENT SEROTONIN TRANSPORTER

Unknown

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