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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CABOTEGRAVIR

CABOTEGRAVIR


ATC J05AJ04

ANTIINFECTIVES
(HIV-1) INTEGRASE STRAND TRANSFER INHIBITOR (INSTI)
ANTIRETROVIRAL DRUG

ORAL INTRAMUSCULAR

Cmax 19.7 MICROMOLAR

Tmax 3 HOUR

PPB 99.8 PERCENT

HT 41 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

HIV-1 INTEGRASE

Integrase UNIPROT Q7ZJM1 pol

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