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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OLICERIDINE
| OLICERIDINE | NERVOUS SYSTEM | INTRAVENOUS | VD 105 LITER PPB 77 PERCENT HT 2.15 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | MU-OPIOID RECEPTOR PDB 8EFB (OLICERIDINE-BOUND MU-OPIOID RECEPTOR-GI COMPLEX) LIGAND CODE = WH2 (link to the list of PDB complexes) Download experimental 3D coordinates of WH2 with added hydrogens | Mu-type opioid receptor UNIPROT P35372 OPRM1 more at DrugCentral | EMA | |||
