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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PRETOMANID

PRETOMANID


ATC J04AK08

ANTIINFECTIVES
NITROIMIDAZOOXAZINE ANTIMYCOBACTERIAL DRUG
TREATMENT OF ADULTS WITH PULMONARY EXTENSIVELY DRUG RESISTANT (XDR) TREATMENT-INTOLERANT OR NONRESPONSIVE MULTIDRUG-RESISTANT (MDR) TUBERCULOSIS (TB)
INHIBITING MYCOLIC ACID BIOSYNTHESIS

ORAL

Cmax 5.5 MICROMOLAR

Tmax 5 HOUR

VD 97 LITER

PPB 86.4 PERCENT

Cl 3.9 LITER / HOUR

HT 17.4 HOUR

Unknown

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