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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CENOBAMATE
| CENOBAMATE | NERVOUS SYSTEM | ORAL | Tmax 2.5 HOUR F 88 PERCENT VD 45 LITER PPB 60 PERCENT Cl 0.54 LITER / HOUR HT 55 HOUR SOLUBILITY VERY SOLUBLE IN AQUEOUS SOLUTIONS (1.7 MILLIGRAM PER MILLILITER) | Gamma-aminobutyric acid receptor subunit alpha-4 UNIPROT P48169 GABRA4 more at DrugCentral | EMA | ||||
