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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SELINEXOR
| SELINEXOR | ANTINEOPLASTIC | ORAL | Cmax 1.53 MICROMOLAR Tmax 4 HOUR VD 125 LITER PPB 95 PERCENT Cl 17.9 LITER / HOUR HT 7 HOUR | EXPORTIN 1 (XPO1) | Exportin-1 UNIPROT O14980 XPO1 more at DrugCentral | EMA | |||
