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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was usedPrimary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
REMIMAZOLAM

REMIMAZOLAM


ATC N05CD14

NERVOUS SYSTEM
BENZODIAZEPINE
INDUCTION AND MAINTENANCE OF PROCEDURAL SEDATION
DID NOT SHOW CLEAR SELECTIVITY BETWEEN SUBTYPES OF THE GABAA RECEPTOR

INTRAVENOUS

Cmax 15.8 MICROMOLAR

VD 56.5 LITER (65 KILOGRAM)

PPB 91 PERCENT

Cl 64.5 LITER / HOUR

HT 0.75 HOUR

SOLUBILITY SPARINGLY SOLUBLE IN WATER

GAMMA AMINO BUTYRIC ACID TYPE A [GABAA] RECEPTOR

GABA-A receptor

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