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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FENFLURAMINE (has an active metabolite)
| FENFLURAMINE | NERVOUS SYSTEM | ORAL | Cmax 294.2 NANOMOLAR Tmax 4.5 HOUR F 71 PERCENT VD 773.5 LITER (65 KILOGRAM) PPB 50 PERCENT Cl 24.8 LITER / HOUR HT 20 HOUR | SEROTONIN TRANSPORTER | Sodium-dependent serotonin transporter UNIPROT P31645 SLC6A4 more at DrugCentral | EMA | |||
