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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| UPADACITINIB
| UPADACITINIB | IMMUNOMODULATING | ORAL | Tmax 3 HOUR PPB 52 PERCENT HT 11 HOUR SOLUBILITY 0.2 TO 38 MILLIGRAM / MILLILITER | JANUS KINASE (JAK) | Tyrosine-protein kinase JAK3 UNIPROT P52333 JAK3 -- Tyrosine-protein kinase JAK1 UNIPROT P23458 JAK1 more at DrugCentral | EMA | |||
